Massive Transfusion

Introduction Massive transfusion is traditionally defined as transfusion of 10 units of packed red blood cells (PRBCs) within a 24 […]

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Tablet with words Pulmonary hypertension and stethoscope.
Understanding Pulmonary hypertension (PH)

Dr Khaled Mohamed Aly provides an informative article of many of the factors surrounding pulmonary hypertension, including: clinical features, causes, risk factors, complications, diagnosis, medication and surgeries.

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Approach to vasopressor medications in shock states

Vasopressors are medications that causes vasoconstriction; some of them have additional inotropic effect. By maintaining end-organ perfusion; the role of vasopressors remains critical to prevent irreversible organ injury and failure, and their use is usually accompanied by fluid resuscitation for adequate patient outcomes. Vasopressor agents are used clinically in the treatment of arterial hypotension in shock states. Shock is best defined as inadequate blood flow to meet the metabolic needs of the tissues. The most common reasons for shock are the cardiac output is low relative to the global demand, despite increased O2 extraction by the tissues; or perfusion pressure is inadequate such that blood flow distribution to metabolically active tissues is inadequate, despite an otherwise adequate cardiac output.

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An insight on critical care in obstetrics - pregnant woman in hospital
An insight on critical care in obstetrics

Pregnancy-related complications constitute a significant part in critical care, in this article Dr Khaled provides an insight on critical care in obstetrics. He highlights that the most common indications for ICU admission are postpartum hemorrhage, pregnancy induced hypertension, and related disorders.

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managemet of gout
New updates in the management of gout

Dr Khaled discusses the advances in the diagnosis and management of gout; the novel urate-lowering therapies, new imaging modalities, and a deeper understanding of the pathogenesis of gout raise the possibility of better gout care and improved patient outcomes and adequate lowering of serum uric acid with minimal effects on renal tissues.

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