Sacubitril/Valsartan in Management of Heart Failure: A Review of Safety, Efficacy and Cost-Effectiveness

This review explores the recommended guidelines on combination therapy with SAC/VAL, advantages and disadvantages of this combination over traditional therapies, and effectiveness and safety of SAC/VAL in patients with HFrEF. Additionally, this review also scrutinizes the cost-effectiveness of SAC/VAL to understand the clinical utility this drug, specifically in developing parts of the world.

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