Palliative care in the Middle East

In the Middle East, the growth of palliative care is still in its early stages. Dr Lama El Zein discusses how providing palliative care has shown to have extensive benefits for patients with serious illnesses by improving quality of life, decreasing unnecessary cost and improving care throughout the illness.

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The Domino Effect of Medical Errors

MEs are associated with a high-rate of morbidity, mortality, and economic burden on the community. Dr Samer Ellahham, (MD, CPHQ, FACMQ, EFQM, FACP, FACC, FAHA, FCCP) highlights the domino effect of medical errors in this must-read article.

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Discovery may lead to precision-based strategy for triple negative breast cancer

According to the paper now available online, TP53 is the most frequently mutated gene in triple negative breast cancer, meaning it is fuelling the growth of this aggressive form of breast cancer. However, the problem with trying to target mutated TP53, specifically, is that it is not a druggable target, because of its potential toxicity – or ability to kill – nearby healthy cells.

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Approach to vasopressor medications in shock states

Vasopressors are medications that causes vasoconstriction; some of them have additional inotropic effect. By maintaining end-organ perfusion; the role of vasopressors remains critical to prevent irreversible organ injury and failure, and their use is usually accompanied by fluid resuscitation for adequate patient outcomes. Vasopressor agents are used clinically in the treatment of arterial hypotension in shock states. Shock is best defined as inadequate blood flow to meet the metabolic needs of the tissues. The most common reasons for shock are the cardiac output is low relative to the global demand, despite increased O2 extraction by the tissues; or perfusion pressure is inadequate such that blood flow distribution to metabolically active tissues is inadequate, despite an otherwise adequate cardiac output.

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LifeTime initiative for revolutionizing global health care

Dr Hoda, attended the 2018 Falling Walls international conference on future breakthroughs in science and society in Berlin, Germany. Along with other 20 eminent participants from various backgrounds and expertise; she was invited to discuss the LifeTime initiative vision from different angles.

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