Alzheimer’s disease is the most common form of age-related dementia, affecting 62% of those diagnosed with dementia and is also a progressive condition; this means the symptoms develop gradually over many years, eventually becoming more and more severe.
The disease is usually characterised by loss of memory and dramatic changes in character and behaviour, eventually leading to an inability to carry out normal daily life activities. The cause of the disease is the accumulation of the toxic beta-amyloid peptide in brain tissue, which leads to oxidative stress, neuroinflammation, mitochondrial dysfunction, and ultimately – the death of nerve cells.
Despite a recent increase in the number of Alzheimer’s patients due to increased longevity and awareness as well as improved diagnosis, there is currently no cure for Alzheimer’s disease. This makes finding a suitable and effective treatment for the condition of the utmost importance.
Researchers from Nazarbayev University and the National Laboratory Astana are investigating the use of mobile phone frequency electromagnetic fields as a form of future treatment for age-related dementia. Specifically, they are studying how radiofrequency electromagnetic fields could be used in Alzheimer’s disease therapy, selecting a frequency of 918 Hz because it is commonly used in mobile phones.
Researcher Andrey Tsoy from the Centre for Life Sciences said: “Building on the work of scientists from the USA, who conducted experiments with the same parameters in a 6-month period, we used human and rat cultures and a shorter exposure period of 60 minutes. The results of our studies, obtained by irradiation of cells with an electromagnetic field frequency of 918 MHz in a period of up to 24 hours, confirmed the ability of the electromagnetic field to suppress oxidative stress, which indicates the possible therapeutic effect.”
The study provides insight into what happens when an electromagnetic field of 918 MHz frequency suppresses oxidative stress triggered by beta-amyloid peptide in brain tissue. The findings suggest that irradiation with an electromagnetic field frequency of 918 MHz shows promise in being used as a treatment for Alzheimer’s patients. Nazarbayev University’s scientists plan to continue research in this direction and confirm whether these methods can be implemented in the fight against the devastating disease.
Credit: Andrey Tsoy
Source: National Laboratory Astana, Nazarbayev University