References

MEMP Magazine July 2018

References

Cancer in Egypt: A special report written by Aalaa Abdou, a Clinical Oncology Specialist in Ministry of Health of Egypt. Page 38.

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  4. Hajdu, Steven I. (alone or with co-authors) “A Note From History: Landmarks in History of Cancer, Part 1~6.” Cancer, v. 117/5, 117/12, v.118/4, v. 118/8, 118/20 & 119/23 (2011-2013).
  5. Zheng YL, Amr S, Saleh D, Dash C, Ezzat S, Mikhail NN, et al. Urinary bladder cancer risk factors in Egypt: a multi-center case-control study. Cancer Epidemiol Biomarkers Prev. 2012;21:537–46.
  6. El-Akel W, El-Sayed MH, El Kassas M, et al. National treatment programme of hepatitis C in Egypt: hepatitis C virus model of care. J Viral Hepat. 2017;24(4):262–267.

Atavistic Chemotherapy: Breaking away from expensive and ineffective cancer drugs, written by Dr Frank Arguello, MD Director of Atavistic Chemotherapy Clinical Trial. Page 44.

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  5. Workman, P., et.al., “How Much Longer Will We Put Up With $100,000 Cancer Drugs?” Cell. 168/4 (2017), 579-583
  6. Prigerson, HG., et.al., “Chemotherapy Use, Performance Status, and Quality of Life at the End of Life,” JAMA Oncol. 1/6 (2015), 778-84
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Compounding tablets in the Middle East: Benefits of small-scale tablet manufacturing systems written by Dr Michael Gamlen. Page 50.

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Non-alcoholic fatty liver disease: Does genetics have a role? Written by Dr Ravi Kanth. Page 62.

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  6. Kozlitina J, Smagris E, Stender S, et al. Exomewide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 2014;46: 352-356.
  7. Holmen OL, Zhang H, Fan Y, et al. Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. Nat Genet 2014; 46: 345-351.
  8. Mahdessian H, Taxiarchis A, Popov S et al. TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. Proc Natl Acad Sci USA 2014; 111: 8913-8918.

Abbreviations used

NAFLD – Non alcoholic fatty liver disease; NASH – Non alcoholic steato hepatitis; HCC – hepatocellular carcinoma; USA – United states of America; IRS-1 –  Insulin Receptor Substrate 1; ENPP1 – Ectonucleotide Pyrophosphatase/Phosphodiesterase 1; GCKR – Glucokinase regulatory protein; PPARG –  peroxisome proliferator-activated receptor; TCF7L2 – Transcription Factor 7 Like 2; SLC2A1 – Solute Carrier Family 2 Member 1; SLC27A5 – Solute Carrier Family 27 Member 5; LIPN1 –  Lipin 1; MTTP – Microsomal Triglyceride Transfer Protein; PEMT –  Phosphatidylethanolamine N-Methyltransferase; ADIPOQ – Adiponectin; APOC3 – Apolipoprotein C3; APOE3 – Apolipoprotein E; NR1/2 (PXR) – Nuclear Receptor Subfamily 1 Group I Member 2; PPARA – Peroxisome Proliferator Activated Receptor  alpha; FADS1 – Fatty Acid Desaturase 1; HFE – Hemochromatosis; SOD2 –  Superoxide Dismutase 2; GCLC – Glutamate-Cysteine Ligase Catalytic Subunit; MRP2 (ABCC2) – Multidrug resistance-associated protein 2; MTHFR – methylenetetrahydrofolate reductase; TNF –  tumor necrosis factor; sTNFr-2 – Tumor necrosis factor receptor 2; FDFT1 – Farnesyl-Diphosphate Farnesyltransferase 1; IL6 – Interleukin 6; AGT – Angiotensinogen; ATGR1 – Angiotensin II Receptor Type 1; KLF6 –  Kruppel Like Factor 6; TGFb1 – Transforming Growth Factor Beta 1; COL13A1 – Collagen Type XIII Alpha 1 Chain; CDKN1A – Cyclin Dependent Kinase Inhibitor 1A; PNPLA3 –  Patatin Like Phospholipase Domain Containing 3; TM6SF2 – Transmembrane 6 Superfamily Member 2

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